Deprescribing research is of international interest due to harms from polypharmacy. Many priorities for deprescribing guidelines have been identified, and research is underway to develop new guidelines and examine uptake and effect on health outcomes. Below are descriptions of work that the team has been involved in.

A Multi-Method Approach to Exploring Prescribing Cascades

Prescribing cascades occur when a drug is used to treat the side effect of another drug. We are studying how and why prescribing cascades start and continue, their impact on people, and how they can be prevented or reversed. Our research began with two series of...

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Deprescribing guidelines – Tools for implementation

Deprescribing can be challenging. The Bruyère and Ontario Pharmacy Evidence Network’s “Deprescribing Guidelines for the Elderly” project developed guidelines and decision-support tools in the form of algorithms. New knowledge translation tools supported by this grant...

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Creating Evidence-based Deprescribing Guidelines

Prescribers have said that it’s difficult to stop medications when prescribing guidelines only talk about starting them. The “Deprescribing Guidelines for the Elderly” project developed evidence-based deprescribing guidelines to support clinicians in safely reducing...

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